Steritest ez system sterility testing of products to be. Methyl tetradecanoate, myristic acid methyl ester cas number 124107. Firstaid measures general advice if symptoms persist, call a physician. Isopropyl myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products. It is generally safe, although some people with skin conditions may wish to avoid products containing. Sample recipe for isopropyl myristate making cosmetics. Long chain fatty acid esters, structurally similar to isopropyl myristate, were rapidly degraded by mixed sewage sludge1,2,3. Other local effects have included nasal and lung irritation during inhalation of aerosols in monkeys and rats, acne development after application to rabbit skin, and increased permeability of human. Isopropyl myristate is found in several everyday beauty products and is generally considered safe for consumer use. Apr 19, 2017 isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Isopropyl myristate is also a great, nontoxic solvent for monster clay. Isopropyl myristate tetradecanoic acid, 1 methylethyl. Isopropyl myristate msds pdf material safety data sheet. Isopropyl myristate 98% isopropyl myristate, 98% min.
Isopropyl myristate safety data sheet according to federal register vol. Tetradecanoic acid, 1methylethyl ester chemical formula. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas. It is also used as a pesticide against head lice which works. Isopropyl myristate, the ester of myristic acid and isopropyl alcohol, is also used in topical medications. Committee to evaluate drugs ced recommendations and reasons this document posted april 2010 isopropyl myristate product. Packaging and storage preserve in tight, lightresistant containers. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Pdf isopropyl myristate production process optimization.
Isopropyl myristate name isopropyl myristate product identification naturalidentical flavouring substance chemical name isopropyl tetradecanoate chemical formulae c17h34o2 cas number 110270 fema number 3556 einecs number 2037514 physicochemical properties aspect colourless liquid organoleptic description. Green synthesis of isopropyl myristate in novel single phase. Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in the closed bottle test4. Material safety data sheet section 1 isopropyl myristate 1 chemical product and company identification msds name. Ipm is used to dissolve lanolin and other oils, and is commonly used as a degreasant or softener in sunscreens, face creams and lipsticks. Apr 27, 2020 isopropyl myristate msds pdf material safety data sheet. Any website that suggests this material is harmful should be ignored. Isopropyl myristate in mumbai, maharashtra get latest price. Effectiveness of isopropyl myristatecyclomethicone d5. Find patient medical information for isopropyl myristate bulk on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pdf enzymatic synthesis of isopropyl myristate using. Viscous products, such as creams and ointments, can be difficult to filter and are normally diluted in a sterile solvent, such as isopropyl myristate ipm.
Isopropyl myristate ipm has produced slight irritation of human skin, mild irritation of the rabbit eye and moderate irritation of rabbit skin. Isopropyl myristate is being studied as a skin enhancer. Isopropyl myristate standard liquid parameters specification test methods identification passes test uspnf appearance passes test inhouse method odor passes test inhouse method acid value, mgkohg 1. Import data and price of isopropyl myristate under hs code. Despite its popularity with manufacturers, some side effects have been reported. Isomyst, stepan d50, bisomel, ipm, tegester, crodamol i. Composed of of isopropyl alcohol a propane derivative and myristic acid a naturallyoccurring fatty acid, isopropyl myristate is a popular cosmetic and pharmaceutical ingredient. Isopropyl myristate revision date 24jan2018 component casno weight % isopropyl myristate 110270 95 4. Chemical product and company identification product name. Isopropyl myristate, present at 100 mgl, reached 94% of its chemical oxygen demand in 28 days using a municipal waste water inoculum in. Isopropyl myristate 110270 1 225 version 2 revision date 07112008 print date 07112008 page 4 8 requirements for storage areas and containers.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrat. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using. Committee to evaluate drugs ced isopropyl myristate. Isopropyl myristate is a light, colorless, oily liquid.
Spectrum chemical nf products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Isopropyl myristate ipm is the ester of isopropyl alcohol and myristic acid. Show this safety data sheet to the doctor in attendance. The substance identity section is calculated from substance identification information from all echa databases. Using a homogeneous reaction phase, nonspecific lipase derived from candida antartica, marketed as novozym 435, was determined to be most suitable for the enzymatic synthesis of isopropyl myristate. Isopropyl myristate can be used to dilute aroma chemicals. Material safety data sheet duke safety office duke university. Isopropyl myristate was used as oil phase in the preparation of formulations. Isopropyl myristate and palmitate are esters formed from isopropyl alcohol and myristic and palmitic acids. Keep containers tightly closed in a dry, cool and wellventilated place.
Isopropyl myristate msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. Isopropyl myristate is a synthetic oil widely used in the cos. Sigmaaldrich offers a number of isopropyl myristate products. Steritest ez system sterility testing of products to be diluted in isopropyl myristate filtration is the pharmacopoeia method of choice for sterility testing. It is widely used as a nontoxic alternative for the control of head lice, as an emollient, and a lubricant. Isopropyl myristate is the ester of isopropyl alcohol and myristic acid. It has been attacked by scaremongers either from ignorance or more likely from a cynical desire to sell inferior products at high prices. These products will have been purified before being used in the cosmetics to remove any residual isopropyl alcohol. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired. Isopropyl myristate ipm makeup and adhesive remover.
Can a product be alcohol free while containing isopropyl. Low viscosity fluid nongreasy emollient, tolerates wide ph range, compatible with most surfactants. Its also perfect as a perfume diluent in place of other oils or alcohol. Aug 30, 2019 isopropyl myristate msds pdf material safety data sheet. Collect and dispose of spillage as indicated in section of the sds. Isopropyl myristate 98% isopropyl tetradecanoate sigmaaldrich. Isopropyl myristate, with the chemical formula ch 3 ch 2 12 cooch ch 3 2, is an ester of myristic acid, an essential fatty acid derived from palm kernel oil and isopropyl alcohol. Enzymatic synthesis of isopropyl myristate using immobilized lipase from bacillus cereus mtcc 8372 article pdf available in acta microbiologica et immunologica hungarica 553. Cetearyl ethylhexanoate and isopropyl myristate shopify. It was also used as oilwatertype tacrolimus fk506 solvent. Its used in cosmetic and topical medicinal preparations. Isopropyl myristate, nf is an emollient ester of low viscosity used to reduce the greasiness of emulsions. Role of isopropyl myristate, isopropyl alcohol and a combination of both in hydrocortisone permeation across the human stratum corneum.
Final report on the safety assessment of myristyl myristate. Mar 21, 2020 isopropyl myristate msds pdf material safety data sheet. Ester of isopropyl alcohol and myristic acid vegetablederived. Used as an emollient and lubricant in preshaves, aftershaves, shampoos, bath oils. Isopropyl myristate, nf 110270 is145 spectrum chemical. Pediculicide widespread and common in children between the ages of 3 and 12.
Isopropyl myristate msds material safety data sheet isopropyl myristate 1. Wear protective clothing as described in section 8 of this safety data sheet. In cosmetics and personal care products, isopropyl myristate functions as a binder, and skinconditioning agent a emollient. Isopropyl myristate resultz 50% topical solution class of drugs. Role of isopropyl myristate, isopropyl alcohol and a. Safety data sheet according to federal register vol. Hallstar ipmnf is a multifunctional emollient, solvent, spreading agent, penetrant synthetically produced ester of vegetal myristic acid and petrochemical isopropyl alcohol that conforms to the requirements of the national formulary monograph for isopropyl myristate. Find out more about isopropyl myristate, all the commercially available products, formulation examples and other related technical info. Isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Isopropyl myristate consists of esters of isopropyl alcohol and saturated high molecular weight fatty acids, principally myristic acid. Isopropyl myristate ipm makeup and adhesive remover stage. Lastly, isopropyl myristate is also believed to have strong skin penetrating properties. This is a valuable attribute, as isopropyl myristate can help other skin healing chemicals to penetrate more deeply. Myristic acid isopropyl ester isopropyl tetradecanoate 1.
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